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As an antihistamine, doxylamine is an inverse agonist of the histamine H 1 receptor. As a first-generation antihistamine, it typically crosses the blood–brain barrier into the brain, thereby producing a suite of sedative and hypnotic effects that are mediated by the central nervous system. (N.b.:
Perinatal stroke. Perinatal stroke is a disease where an infant has a stroke between the 140th day of the gestation period and the 28th postpartum day, [ 1] affecting up to 1 in 2300 live births. [ 2] This disease is further divided into three subgroups, namely neonatal arterial ischemic stroke, neonatal cerebral sinovenous ischemic stroke, and ...
An elevated level of stress during pregnancy leads to notorious pregnancy outcomes, including preterm birth, low birth weight, and mental health problems for the mother. Prolonged effects of chronic stressors such as discrimination, intimate partner violence, housing issues, and poverty lead to widespread maternal health issues and adverse ...
Pyridoxine/doxylamine, sold under the brand name Diclectin among others, is a combination of pyridoxine hydrochloride (vitamin B 6) and doxylamine succinate.It is generally used for nausea and vomiting of pregnancy (morning sickness); even though its efficacy has not been proven and subsequent research has led to the removal of recommendations in medical journals.
Cerebral infarction, also known as an ischemic stroke, is the pathologic process that results in an area of necrotic tissue in the brain (cerebral infarct). [ 1] In mid to high income countries, a stroke is the main reason for disability among people and the 2nd cause of death. [ 2]
Amniotic fluid embolism is suspected when a woman giving birth experiences very sudden insufficient oxygen to body tissues, low blood pressure, and profuse bleeding due to defects in blood coagulation . The signs and symptoms of amniotic fluid embolism can vary from one individual to another but involve systemic involvement of multiple organ ...
Carpal tunnel syndrome – Carpal tunnel syndrome can occur in up to 70% of pregnant women and typically has a benign course. [16] [17] It manifests as pain, numbness, and tingling in the thumb, index finger, middle finger and the thumb side of the ring finger. [18] The symptoms of carpal tunnel syndrome during pregnancy are usually mild and do ...
Sheehan's syndrome, also known as postpartum pituitary gland necrosis, occurs when the pituitary gland is damaged due to significant blood loss and hypovolemic shock (ischemic necrosis) usually during or after childbirth leading to decreased functioning of the pituitary gland ( hypopituitarism ). [ 1] The pituitary gland is an endocrine organ ...