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Homatropine (Equipin, Isopto Homatropine) is an anticholinergic medication that is an antagonist at muscarinic acetylcholine receptors and thus the parasympathetic nervous system. It is used in eye drops as a cycloplegic (to temporarily paralyze accommodation ), and as a mydriatic (to dilate the pupil ).
Cyclopentolate is a muscarinic antagonist. [ 2] It is commonly used as an eye drop during pediatric eye examinations to dilate the eye ( mydriatic) and prevent the eye from focusing/ accommodating ( cycloplegic ). Cyclopentolate [citation needed] or atropine can also be administered to reverse muscarinic and central nervous system effects of ...
Tropicamide, sold under the brand name Mydriacyl among others, is a medication used to dilate the pupil and help with examination of the eye. [ 3] Specifically it is used to help examine the back of the eye. [ 4] It is applied as eye drops. [ 3] Effects occur within 40 minutes and last for up to a day.
Homatropine methylbromide ( INN; also known as methylhomatropine bromide) is a quaternary ammonium salt of methylhomatropine. It is a peripherally acting anticholinergic medication that inhibits muscarinic acetylcholine receptors and thus the parasympathetic nervous system. It does not cross the blood–brain barrier.
Cycloplegia. Cycloplegia is paralysis of the ciliary muscle of the eye, resulting in a loss of accommodation. [1] Because of the paralysis of the ciliary muscle, the curvature of the lens can no longer be adjusted to focus on nearby objects. This results in similar problems as those caused by presbyopia, in which the lens has lost elasticity ...
Netarsudil. Netarsudil, sold under the brand name Rhopressa among others, is a medication for the treatment of glaucoma. [ 1][ 2][ 3] In the United States, in December 2017, the Food and Drug Administration (FDA) approved a 0.02% ophthalmic solution for the lowering of elevated intraocular pressure in people with open-angle glaucoma or ocular ...
For symptomatic bradycardia, the usual dosage is 0.5 to 1 mg IV push; this may be repeated every 3 to 5 minutes, up to a total dose of 3 mg (maximum 0.04 mg/kg). [ 23 ] Atropine is also useful in treating second-degree heart block Mobitz type 1 (Wenckebach block) , and also third-degree heart block with a high Purkinje or AV-nodal escape rhythm .
Clinical trial number NCT03751631 for "Safety and Efficacy of Phenylephrine 2.5%-Tropicamide 1% Microdose Ophthalmic Solution for Pupil Dilation (MIST-1)" at ClinicalTrials.gov; Clinical trial number NCT03751098 for "Safety and Efficacy of Phenylephrine 2.5%-Tropicamide 1% Microdose Ophthalmic Solution for Pupil Dilation (MIST-2)" at ...