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Homatropine (Equipin, Isopto Homatropine) is an anticholinergic medication that is an antagonist at muscarinic acetylcholine receptors and thus the parasympathetic nervous system. It is used in eye drops as a cycloplegic (to temporarily paralyze accommodation ), and as a mydriatic (to dilate the pupil ).
Netarsudil. Netarsudil, sold under the brand name Rhopressa among others, is a medication for the treatment of glaucoma. [ 1][ 2][ 3] In the United States, in December 2017, the Food and Drug Administration (FDA) approved a 0.02% ophthalmic solution for the lowering of elevated intraocular pressure in people with open-angle glaucoma or ocular ...
Cyclopentolate is a muscarinic antagonist. [ 2] It is commonly used as an eye drop during pediatric eye examinations to dilate the eye ( mydriatic) and prevent the eye from focusing/ accommodating ( cycloplegic ). Cyclopentolate [citation needed] or atropine can also be administered to reverse muscarinic and central nervous system effects of ...
For symptomatic bradycardia, the usual dosage is 0.5 to 1 mg IV push; this may be repeated every 3 to 5 minutes, up to a total dose of 3 mg (maximum 0.04 mg/kg). [ 23 ] Atropine is also useful in treating second-degree heart block Mobitz type 1 (Wenckebach block) , and also third-degree heart block with a high Purkinje or AV-nodal escape rhythm .
Homatropine methylbromide ( INN; also known as methylhomatropine bromide) is a quaternary ammonium salt of methylhomatropine. It is a peripherally acting anticholinergic medication that inhibits muscarinic acetylcholine receptors and thus the parasympathetic nervous system. It does not cross the blood–brain barrier.
Tropicamide, sold under the brand name Mydriacyl among others, is a medication used to dilate the pupil and help with examination of the eye. [ 3] Specifically it is used to help examine the back of the eye. [ 4] It is applied as eye drops. [ 3] Effects occur within 40 minutes and last for up to a day.
Cycloplegia. Cycloplegia is paralysis of the ciliary muscle of the eye, resulting in a loss of accommodation. [1] Because of the paralysis of the ciliary muscle, the curvature of the lens can no longer be adjusted to focus on nearby objects. This results in similar problems as those caused by presbyopia, in which the lens has lost elasticity ...
Twice daily in right eye 26 weeks 1.0% No mortality at all doses. After ocular administration, symptoms included hypermia of the bulbar and papebral conjunctiva, white spots in the lens. Dogs Once a day in right eye and orally 13 weeks 2.0% in eye, 7.5 mg/kg/day by mouth No mortality observed. Monkey Once a day in right eye 52 weeks 2.0%