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Pregnenolone ( P5 ), or pregn-5-en-3β-ol-20-one, is an endogenous steroid and precursor / metabolic intermediate in the biosynthesis of most of the steroid hormones, including the progestogens, androgens, estrogens, glucocorticoids, and mineralocorticoids. [ 1]
Prednisolone acetate is acutely toxic with an LD50 of >240 mg/kg for a rat and 3500 mg/kg for a mouse. Effects may present delayed. Target organs include adrenal cortex, bones, and eyes. It is also a known teratogen. [3] Class B PPE should be worn when working with this chemical. Any contact with this chemical should be taken seriously and the ...
Prednisolone is a corticosteroid drug with predominant glucocorticoid and low mineralocorticoid activity, making it useful for the treatment of a wide range of inflammatory and autoimmune conditions [14] such as asthma, [15] uveitis, pyoderma gangrenosum, rheumatoid arthritis, urticaria, [16] angioedema, [16] ulcerative colitis, pericarditis, temporal arteritis and Crohn's disease, Bell's ...
Pregnenolone acetate (brand names Antofin, Previsone, Pregno-Pan ), also known as pregn-5-en-3β-ol-20-one 3β-acetate, is a synthetic pregnane steroid and an ester of pregnenolone which is described as a glucocorticoid and as a skin-conditioning and skin anti-aging agent. [2] [3] It has been reported to reduce wrinkles in elderly women when ...
Mometasone. Mometasone, also known as mometasone y 3 s, is a steroid (specifically, a glucocorticoid) medication used to treat certain skin conditions, hay fever, and asthma. [ 8][ 9][ 10] Specifically it is used to prevent rather than treat asthma attacks. [ 8]
Pregnenolone is a neurosteroid. [5] [6] It is a negative allosteric modulator of the CB 1 receptor, [5] [8] a ligand of the microtubule-associated protein 2 (MAP2), [9] [10] and an agonist of the pregnane X receptor. [11] Pregnenolone has no progestogenic, corticosteroid, estrogenic, androgenic, or antiandrogenic activity. [3]
Dexamethasone is a fluorinated glucocorticoid medication [10] used to treat rheumatic problems, a number of skin diseases, severe allergies, asthma, chronic obstructive lung disease, croup, brain swelling, eye pain following eye surgery, superior vena cava syndrome (a complication of some forms of cancer), [11] and along with antibiotics in tuberculosis. [10]
Fluoxymesterone. Fluoxymesterone, sold under the brand names Halotestin and Ultandren among others, is an androgen and anabolic steroid (AAS) medication which is used in the treatment of low testosterone levels in men, delayed puberty in boys, breast cancer in women, and anemia. [ 1] It is taken by mouth.
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