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Tissue-type plasminogen activator. Tissue-type plasminogen activator, short name tPA, is a protein that facilitates the breakdown of blood clots. It acts as an enzyme to convert plasminogen into its active form plasmin, the major enzyme responsible for clot breakdown. It is a serine protease ( EC 3.4.21.68) found on endothelial cells lining the ...
Alteplase, sold under the brand name Activase among others, is a biosynthetic form of human tissue-type plasminogen activator (t-PA). It is a thrombolytic medication used to treat acute ischemic stroke, acute ST-elevation myocardial infarction (a type of heart attack), pulmonary embolism associated with low blood pressure, and blocked central venous catheter. [5]
Tenecteplase. Tenecteplase, sold under the trade names TNKase, Metalyse and Elaxim, is an enzyme used as a thrombolytic drug . Tenecteplase is a tissue plasminogen activator (tPA) produced by recombinant DNA technology using an established mammalian cell line ( Chinese hamster ovary cells ). Tenecteplase is a 527 amino acid glycoprotein ...
Third-party administrator. In the United States, a third-party administrator ( TPA) is an organization that processes insurance claims or certain aspects of employee benefit plans for a separate entity. [ 1] It is also a term used to define organizations within the insurance industry which administer other services such as underwriting and ...
Brainrot is a special segment of Gen Alpha slang that comes from spending a ton of time online —usually in spaces like TikTok, Snapchat, YouTube, or even gaming communities like Roblox or ...
Infobox references. 12-O-Tetradecanoylphorbol-13-acetate ( TPA ), also commonly known as tetradecanoylphorbol acetate, tetradecanoyl phorbol acetate, and phorbol 12-myristate 13-acetate ( PMA) is a diester of phorbol. It is a potent tumor promoter often employed in biomedical research to activate the signal transduction enzyme protein kinase C ...
Plasminogen activators are serine proteases that catalyze the activation of plasmin via proteolytic cleavage of its zymogen form plasminogen. Plasmin is an important factor in fibrinolysis, the breakdown of fibrin polymers formed during blood clotting. There are two main plasminogen activators: urokinase (uPA) and tissue plasminogen activator ...
The Uncensored Library is a Minecraft server and map released by Reporters Without Borders (RSF) and created by BlockWorks, DDB Berlin, [1] and Media.Monks [2] as an attempt to circumvent censorship in countries without freedom of the press. The library contains banned reporting from Mexico, Russia, Vietnam, Saudi Arabia, Egypt, Brazil, and ...