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Homatropine (Equipin, Isopto Homatropine) is an anticholinergic medication that is an antagonist at muscarinic acetylcholine receptors and thus the parasympathetic nervous system. It is used in eye drops as a cycloplegic (to temporarily paralyze accommodation ), and as a mydriatic (to dilate the pupil ).
A spasm of accommodation (also known as a ciliary spasm, an accommodation, or accommodative spasm) is a condition in which the ciliary muscle of the eye remains in a constant state of contraction. Normal accommodation allows the eye to "accommodate" for near-vision. However, in a state of perpetual contraction, the ciliary muscle cannot relax ...
Phenylephrine is used as an eye drop to dilate the pupil to facilitate visualization of the retina. It is often used in combination with tropicamide as a synergist when tropicamide alone is not sufficient. Narrow-angle glaucoma is a contraindication to phenylephrine use. As a mydriatic, it is available in 2.5% and 10% eye drops.
Cyclopentolate is a muscarinic antagonist. [ 2] It is commonly used as an eye drop during pediatric eye examinations to dilate the eye ( mydriatic) and prevent the eye from focusing/ accommodating ( cycloplegic ). Cyclopentolate [citation needed] or atropine can also be administered to reverse muscarinic and central nervous system effects of ...
Tropicamide, sold under the brand name Mydriacyl among others, is a medication used to dilate the pupil and help with examination of the eye. [ 3] Specifically it is used to help examine the back of the eye. [ 4] It is applied as eye drops. [ 3] Effects occur within 40 minutes and last for up to a day.
Pilocarpine is a drug that acts as a muscarinic receptor agonist. It acts on a subtype of muscarinic receptor ( M 3) found on the iris sphincter muscle, causing the muscle to contract - resulting in pupil constriction ( miosis ). Pilocarpine also acts on the ciliary muscle and causes it to contract. When the ciliary muscle contracts, it opens ...
Leptospirosis. Leptospirosis is a blood infection caused by the bacteria Leptospira [ 8] that can infect humans, dogs, rodents and many other wild and domesticated animals. [ 8] Signs and symptoms can range from none to mild ( headaches, muscle pains, and fevers) to severe ( bleeding in the lungs or meningitis ). [ 5]
Clinical trial number NCT03751631 for "Safety and Efficacy of Phenylephrine 2.5%-Tropicamide 1% Microdose Ophthalmic Solution for Pupil Dilation (MIST-1)" at ClinicalTrials.gov; Clinical trial number NCT03751098 for "Safety and Efficacy of Phenylephrine 2.5%-Tropicamide 1% Microdose Ophthalmic Solution for Pupil Dilation (MIST-2)" at ...