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Melatonin, also known as N -acetyl-5-methoxytryptamine, is a substituted tryptamine and a derivative of serotonin (5-hydroxytryptamine). It is structurally related to N-acetylserotonin (normelatonin; N -acetyl-5-hydroxytryptamine), which is the chemical intermediate between serotonin and melatonin in the body.
Melatonin, an indoleamine, is a natural compound produced by various organisms, including bacteria and eukaryotes. [ 1] Its discovery in 1958 by Aaron B. Lerner and colleagues stemmed from the isolation of a substance from the pineal gland of cows that could induce skin lightening in common frogs.
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Treatment. Cognitive behavioral therapy, caffeine (to induce alertness), sleeping pills. Sleep deprivation, also known as sleep insufficiency[ 2] or sleeplessness, is the condition of not having adequate duration and/or quality of sleep to support decent alertness, performance, and health. It can be either chronic or acute and may vary widely ...
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