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2. Melatonin as a medication and supplement - Wikipedia

   en.wikipedia.org/wiki/Melatonin_as_a_medication...

   Melatonin, also known as N -acetyl-5-methoxytryptamine, is a substituted tryptamine and a derivative of serotonin (5-hydroxytryptamine). It is structurally related to N-acetylserotonin (normelatonin; N -acetyl-5-hydroxytryptamine), which is the chemical intermediate between serotonin and melatonin in the body.

3. Hydroxyzine - Wikipedia

   en.wikipedia.org/wiki/Hydroxyzine

   Common side effects include sleepiness, headache, and a dry mouth. [8] [9] Serious side effects may include QT prolongation. [9] It is unclear if use during pregnancy or breastfeeding is safe. [8] Hydroxyzine works by blocking the effects of histamine. [9] It is a first-generation antihistamine in the piperazine family of chemicals. [8] [4]

4. Zolpidem - Wikipedia

   en.wikipedia.org/wiki/Zolpidem

   Zolpidem is a nonbenzodiazepine or Z-drug which acts as a sedative and hypnotic. [ 10][ 16] Zolpidem is a GABA A receptor agonist of the imidazopyridine class. [ 10] It works by increasing GABA effects in the central nervous system by binding to GABA A receptors at the same location as benzodiazepines. [ 10]

5. Mirtazapine - Wikipedia

   en.wikipedia.org/wiki/Mirtazapine

   Mirtazapine is a tetracyclic piperazinoazepine; mianserin was developed by the same team of organic chemists and mirtazapine differs from it via addition of a nitrogen atom in one of the rings. [ 114]: 429 [ 115][ 116] It is a racemic mixture of enantiomers. The ( S )- (+)-enantiomer is known as esmirtazapine .

6. New test may tell who is prone to side effects from ... - AOL

   www.aol.com/test-may-tell-prone-side-153000197.html

   APOE-e4 gene increases ARIA side effect risk. In addition to having an increased risk for Alzheimer’s disease, Sabalza said people with the APOE-e4 allele are also more likely to experience the ...

7. Ramelteon - Wikipedia

   en.wikipedia.org/wiki/Ramelteon

   Ramelteon is taken by mouth. [ 3] Side effects of ramelteon include somnolence, dizziness, fatigue, nausea, exacerbated insomnia, and changes in hormone levels. [ 3] Ramelteon is an analogue of melatonin and is a selective agonist of the melatonin MT 1 and MT 2 receptors. [ 3] The half-life and duration of ramelteon are much longer than those ...

8. Temazepam - Wikipedia

   en.wikipedia.org/wiki/Temazepam

   In medical literature from Australia, Ireland, the UK, Canada, and the United States, temazepam is the only benzodiazepine which has been fatal in overdoses without combination with other CNS depresssants. This unique feature is due to the toxicity of the drug, which numerous studies have ranked it as being most toxic.

9. Trazodone - Wikipedia

   en.wikipedia.org/wiki/Trazodone

   Trazodone's potent α 1-adrenergic blockade may cause some side effects like orthostatic hypotension and sedation. [114] Conversely, along with 5-HT 2A and H 1 receptor antagonism, it may contribute to its efficacy as a hypnotic. Trazodone lacks any affinity for the muscarinic acetylcholine receptors, so does not produce anticholinergic side ...