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Rilmenidine, an oxazoline compound with antihypertensive properties, acts on both medullary and peripheral vasomotor structures. Rilmenidine shows greater selectivity for imidazoline receptors than for cerebral alpha2-adrenergic receptors, distinguishing it from reference alpha2-agonists, and conferring additional anti-inflammatory actions not shared with most other antihypertensive drugs.
When two drugs affect each other, it is a drug–drug interaction (DDI). The risk of a DDI increases with the number of drugs used. [ 1] A large share of elderly people regularly use five or more medications or supplements, with a significant risk of side-effects from drug–drug interactions. [ 2]
Fenbendazole. Fenbendazole (also known as Fenben) is a broad spectrum benzimidazole anthelmintic used against gastrointestinal parasites including: giardia, roundworms, hookworms, whipworms, the tapeworm genus Taenia (but not effective against Dipylidium caninum, a common dog tapeworm), pinworms, aelurostrongylus, paragonimiasis, strongyles ...
Metamizole. Urine (96%, IV; 85%, oral), faeces (4%, IV). [ 4] Metamizole or dipyrone is a painkiller, spasm reliever, and fever reliever drug. It is most commonly given by mouth or by intravenous infusion. [ 13][ 11][ 14] It belongs to the ampyrone sulfonate family of medicines and was patented in 1922.
Tramadol. Tramadol, sold under the brand name Ultram among others, [ 1] is an opioid pain medication and a serotonin–norepinephrine reuptake inhibitor (SNRI) used to treat moderately severe pain. [ 3][ 14] When taken by mouth in an immediate-release formulation, the onset of pain relief usually begins within an hour. [ 3]
An adverse drug reaction ( ADR) is a harmful, unintended result caused by taking medication. [ 1 ]: 1.1 Adverse Drug Reaction (ADR)[ 2 ] ADRs may occur following a single dose or prolonged administration of a drug or may result from the combination of two or more drugs. The meaning of this term differs from the term " side effect " because side ...
Prescription cascade is the process whereby the side effects of drugs are misdiagnosed as symptoms of another problem, resulting in further prescriptions and further side effects and unanticipated drug interactions, which itself may lead to further symptoms and further misdiagnoses. This is a pharmacological example of a feedback loop.
Levocetirizine. Levocetirizine, sold under the brand name Xyzal, among others, is a second-generation antihistamine used for the treatment of allergic rhinitis (hay fever) and long-term hives of unclear cause. [ 3] It is less sedating than older antihistamines. [ 4] It is taken by mouth.
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