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Colesevelam is part of a class of drugs known as bile acid sequestrants. Colesevelam hydrochloride, the active pharmaceutical ingredient in Welchol, is a non-absorbed, lipid-lowering polymer that binds bile acids in the intestine, impeding their reabsorption. As the bile acid pool becomes depleted, the hepatic enzyme, cholesterol 7-α ...
The side effects of cyproterone acetate (CPA), a steroidal antiandrogen and progestin, including its frequent and rare side effects, have been studied and characterized.It is generally well-tolerated and has a mild side-effect profile, regardless of dosage, when it used as a progestin or antiandrogen in combination with an estrogen such as ethinylestradiol or estradiol valerate in women.
In 2001, the FDA changed the labeling requirements for droperidol injection to include a Black Box Warning, citing concerns of QT prolongation and torsades de pointes.The evidence for this is disputed, with 9 reported cases of torsades in 30 years and all of those having received doses in excess of 5 mg. [9] QT prolongation is a dose-related effect, [10] and it appears that droperidol is not a ...
02:45. Semaglutide for weight loss has been in shortage since 2022, according to the FDA’s drug shortage database. Tirzepatide, which was approved for weight loss in the U.S. only in November ...
“It is important to understand that demonizing sugar and broadly categorizing it as ‘toxic’’ or ‘to avoid at all costs’ is typically not helpful, sustainable, or necessary.
Megestrol acetate is a weak partial agonist of the androgen receptor (AR). [ 121][ 122][ 123] It has been reported to bind to this receptor with 5% of the affinity of the anabolic steroid metribolone. [ 2][ 4][ 80] Despite its weak intrinsic activity at the androgen receptor, at clinical doses in humans, megestrol acetate appears to behave, for ...
LONDON (Reuters) -U.S. patients are on average staying on Novo Nordisk's Wegovy weight-loss medication for just six months, an executive said on Wednesday, attributing the short time to the low ...
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