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  2. In vivo - Wikipedia

    en.wikipedia.org/wiki/In_vivo

    In vivo vs. ex vivo research. In microbiology, in vivo is often used to refer to experimentation done in a whole organism, rather than in live isolated cells, for example, cultured cells derived from biopsies. In this situation, the more specific term is ex vivo. Once cells are disrupted and individual parts are tested or analyzed, this is ...

  3. Animal testing - Wikipedia

    en.wikipedia.org/wiki/Animal_testing

    Animal testing, also known as animal experimentation, animal research, and in vivo testing, is the use of non-human animals, such as model organisms, in experiments that seek to control the variables that affect the behavior or biological system under study. This approach can be contrasted with field studies in which animals are observed in ...

  4. In vitro - Wikipedia

    en.wikipedia.org/wiki/In_vitro

    Definition. In vitro ( Latin for "in glass"; often not italicized in English usage [ 3][ 4][ 5]) studies are conducted using components of an organism that have been isolated from their usual biological surroundings, such as microorganisms, cells, or biological molecules. For example, microorganisms or cells can be studied in artificial culture ...

  5. Ex vivo - Wikipedia

    en.wikipedia.org/wiki/Ex_vivo

    Ex vivo brainstem: (A) coronal view displaying the anterior portion of the tissue sample, (B) sagittal view displaying the left-hand side of the tissue sample [ 1] Ex vivo ( Latin: "out of the living") literally means that which takes place outside an organism. [ 2] In science, ex vivo refers to experimentation or measurements done in or on ...

  6. Bioassay - Wikipedia

    en.wikipedia.org/wiki/Bioassay

    A bioassay is an analytical method to determine the potency or effect of a substance by its effect on living animals or plants ( in vivo ), or on living cells or tissues ( in vitro ). [ 1][ 2] A bioassay can be either quantal or quantitative, direct or indirect. [ 3] If the measured response is binary, the assay is quantal; if not, it is ...

  7. Staining - Wikipedia

    en.wikipedia.org/wiki/Staining

    In vivo vs In vitro. In vivo staining (also called vital staining or intravital staining) is the process of dyeing living tissues. By causing certain cells or structures to take on contrasting colours, their form ( morphology) or position within a cell or tissue can be readily seen and studied. The usual purpose is to reveal cytological details ...

  8. Directed evolution - Wikipedia

    en.wikipedia.org/wiki/Directed_evolution

    Directed evolution is a mimic of the natural evolution cycle in a laboratory setting. Evolution requires three things to happen: variation between replicators, that the variation causes fitness differences upon which selection acts, and that this variation is heritable. In DE, a single gene is evolved by iterative rounds of mutagenesis ...

  9. Coagulation - Wikipedia

    en.wikipedia.org/wiki/Coagulation

    Blood coagulation pathways in vivo showing the central role played by thrombin. Health. Beneficial. Coagulation, also known as clotting, is the process by which blood changes from a liquid to a gel, forming a blood clot. It results in hemostasis, the cessation of blood loss from a damaged vessel, followed by repair.