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  2. Diphenhydramine - Wikipedia

    en.wikipedia.org/wiki/Diphenhydramine

    Diphenhydramine ( DPH) is an antihistamine and sedative mainly used to treat allergies, insomnia, and symptoms of the common cold. It is also less commonly used for tremors in parkinsonism, and nausea. [ 11] It is taken by mouth, injected into a vein, injected into a muscle, or applied to the skin. [ 11]

  3. Benzodiazepine withdrawal syndrome - Wikipedia

    en.wikipedia.org/wiki/Benzodiazepine_withdrawal...

    t. e. Benzodiazepine withdrawal syndrome ( BZD withdrawal) is the cluster of signs and symptoms that may emerge when a person who has been taking benzodiazepines as prescribed develops a physical dependence on them and then reduces the dose or stops taking them without a safe taper schedule .

  4. Doxylamine - Wikipedia

    en.wikipedia.org/wiki/Doxylamine

    As an antihistamine, doxylamine is an inverse agonist of the histamine H 1 receptor. As a first-generation antihistamine, it typically crosses the blood–brain barrier into the brain, thereby producing a suite of sedative and hypnotic effects that are mediated by the central nervous system. (N.b.:

  5. Drug withdrawal - Wikipedia

    en.wikipedia.org/wiki/Drug_withdrawal

    Psychiatry. Drug withdrawal, drug withdrawal syndrome, or substance withdrawal syndrome, [ 1] is the group of symptoms that occur upon the abrupt discontinuation or decrease in the intake of pharmaceutical or recreational drugs . In order for the symptoms of withdrawal to occur, one must have first developed a form of drug dependence.

  6. Recreational use of dextromethorphan - Wikipedia

    en.wikipedia.org/wiki/Recreational_use_of_dext...

    Recreational use of dextromethorphan. Dextromethorphan, or DXM, a common active ingredient found in many over-the-counter cough suppressant cold medicines, is used as a recreational drug and entheogen for its dissociative effects. [ 1] Street names include Brownies, Dextro, Drix, Gel, Groove, Lean, Mega-perls, Poor man's ecstasy, Red devils ...

  7. Temazepam - Wikipedia

    en.wikipedia.org/wiki/Temazepam

    Abrupt withdrawal from therapeutic doses of temazepam after long-term use may result in a severe benzodiazepine withdrawal syndrome. Gradual and careful reduction of the dosage, preferably with a long-acting benzodiazepine with long half-life active metabolites , such as chlordiazepoxide or diazepam , are recommended to prevent severe ...

  8. Nonbenzodiazepine - Wikipedia

    en.wikipedia.org/wiki/Nonbenzodiazepine

    Chemical structure of the prototypical Z-drug zolpidem. Nonbenzodiazepines (/ ˌ n ɒ n ˌ b ɛ n z oʊ d aɪ ˈ æ z ɪ p iː n,-ˈ eɪ-/ [1] [2]), sometimes referred to colloquially as Z-drugs (as many of their names begin with the letter "z"), are a class of psychoactive, depressant, sedative, hypnotic, anxiolytic drugs that are benzodiazepine-like in uses, such as for treating insomnia [3 ...

  9. Anticholinergic - Wikipedia

    en.wikipedia.org/wiki/Anticholinergic

    Anticholinergic. Anticholinergics ( anticholinergic agents) are substances that block the action of the acetylcholine (ACh) neurotransmitter at synapses in the central and peripheral nervous system. [ 1][ 2] These agents inhibit the parasympathetic nervous system by selectively blocking the binding of ACh to its receptor in nerve cells.