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A parathyroid adenoma is a benign tumor of the parathyroid gland. It generally causes hyperparathyroidism; there are very few reports of parathyroid adenomas that were not associated with hyperparathyroidism. [ 1] A human being usually has four parathyroid glands located on the posterior surface of the thyroid in the neck.
The most common cause of primary hyperparathyroidism is a sporadic, single parathyroid adenoma [5] resulting from a clonal mutation (~97%). Less common are parathyroid hyperplasia [6] (~2.5%), parathyroid carcinoma (malignant tumor), and adenomas in more than one gland (together ~0.5%).Primary hyperparathyroidism is also a feature of several familial endocrine disorders: Multiple endocrine ...
Papillary renal cell carcinoma (PRCC) is a malignant, heterogeneous tumor originating from renal tubular epithelial cells of the kidney, which comprises approximately 10-15% of all kidney neoplasms. [ 1 ] Based on its morphological features, PRCC can be classified into two main subtypes, which are type 1 ( basophilic) and type 2 ( eosinophilic ).
Hyperparathyroidism is an increase in parathyroid hormone (PTH) levels in the blood. [ 1][ 4] This occurs from a disorder either within the parathyroid glands ( primary hyperparathyroidism) or as response to external stimuli ( secondary hyperparathyroidism ). [ 1] Symptoms of hyperparathyroidism are caused by inappropriately normal or elevated ...
22.1 million (2015) [ 5] Deaths. 16,100 (2015) [ 6] Kidney stone disease, also known as renal calculus disease, nephrolithiasis or urolithiasis, is a crystallopathy where a solid piece of material ( renal calculus) develops in the urinary tract. [ 2] Renal calculi typically form in the kidney and leave the body in the urine stream. [ 2]
Kidney cancer, also known as renal cancer, is a group of cancers that starts in the kidney. [ 4] Symptoms may include blood in the urine, a lump in the abdomen, or back pain. [ 1][ 2][ 3] Fever, weight loss, and tiredness may also occur. [ 1][ 2][ 3] Complications can include spread to the lungs or brain. [ 6]
Nephrocalcinosis, once known as Albright's calcinosis after Fuller Albright, is a term originally used to describe the deposition of poorly soluble calcium salts in the renal parenchyma due to hyperparathyroidism. The term nephrocalcinosis is used to describe the deposition of both calcium oxalate and calcium phosphate. [ 1]
Frontal MRI four days after MRgFUS (MRI-guided high-intensity focused ultrasound): Left ventral intermediate nucleus (Vim) thalamotomy. 79-year-old man with essential tremor. One of the first applications of HIFU was the treatment of Parkinson's disease in the 1940s. Although ineffective at the time, HIFU has the capacity to lesion pathology.