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Ofloxacin is a racemic mixture, which consists of 50% levofloxacin (the biologically active component) and 50% of its “mirror image” or enantiomer dextrofloxacin. [ 52] "After multiple-dose administration of 200 mg and 300 mg doses, peak serum levels of 2.2 and 3.6 μg/ml, respectively, are predicted at steady-state.
Oncology. Non-small-cell lung cancer ( NSCLC ), or non-small-cell lung carcinoma, is any type of epithelial lung cancer other than small-cell lung cancer (SCLC). NSCLC accounts for about 85% of all lung cancers. [ 1][ 2][ 3] As a class, NSCLCs are relatively insensitive to chemotherapy, compared to small-cell carcinoma.
Small-cell carcinoma is a type of highly malignant cancer that most commonly arises within the lung, [ 1] although it can occasionally arise in other body sites, such as the cervix, [ 2] prostate, [ 3] and gastrointestinal tract. Compared to non-small cell carcinoma, small cell carcinoma is more aggressive, with a shorter doubling time, higher ...
Lung cancer is the most diagnosed and deadliest cancer worldwide, with 2.2 million cases in 2020 resulting in 1.8 million deaths. [3] Lung cancer is rare in those younger than 40; the average age at diagnosis is 70 years, and the average age at death 72. [2] Incidence and outcomes vary widely across the world, depending on patterns of tobacco use.
Ciprofloxacin is a fluoroquinolone antibiotic used to treat a number of bacterial infections. [5] This includes bone and joint infections, intra-abdominal infections, certain types of infectious diarrhea, respiratory tract infections, skin infections, typhoid fever, and urinary tract infections, among others. [5]
Adenocarcinoma of the lung. A gross pathological specimen of a pulmonary adenocarcinoma, removed in a lobectomy. Adenocarcinoma of the lung is the most common type of lung cancer, and like other forms of lung cancer, it is characterized by distinct cellular and molecular features. [ 1] It is classified as one of several non-small cell lung ...
Otitis externa. A moderate case of otitis externa. There is narrowing of the ear channel, with a small amount of exudate and swelling of the outer ear. Otitis externa, also called swimmer's ear, [ 1] is inflammation of the ear canal. [ 2] It often presents with ear pain, swelling of the ear canal, and occasionally decreased hearing. [ 2]
Treatment-related adverse effects in AOE studies were determined in phase II and III trials. This includes ear pruritus, ear debris, superimposed ear infection, ear congestion, ear pain, and erythema. Similar effects were demonstrated in AOMT studies. Overall, Ciprodex was determined as a safe and well-tolerated drug for the treatment of AOE ...