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Ofloxacin is a racemic mixture, which consists of 50% levofloxacin (the biologically active component) and 50% of its “mirror image” or enantiomer dextrofloxacin. [ 52] "After multiple-dose administration of 200 mg and 300 mg doses, peak serum levels of 2.2 and 3.6 μg/ml, respectively, are predicted at steady-state.
Treatment-related adverse effects in AOE studies were determined in phase II and III trials. This includes ear pruritus, ear debris, superimposed ear infection, ear congestion, ear pain, and erythema. Similar effects were demonstrated in AOMT studies. Overall, Ciprodex was determined as a safe and well-tolerated drug for the treatment of AOE ...
Ciprofloxacin is a fluoroquinolone antibiotic used to treat a number of bacterial infections. [5] This includes bone and joint infections, intra-abdominal infections, certain types of infectious diarrhea, respiratory tract infections, skin infections, typhoid fever, and urinary tract infections, among others. [5]
Otitis externa, also called swimmer's ear, [1] is inflammation of the ear canal. [2] It often presents with ear pain, swelling of the ear canal, and occasionally decreased hearing. [2] Typically there is pain with movement of the outer ear. [3] A high fever is typically not present except in severe cases. [3]
Otitis media. Otitis media is a group of inflammatory diseases of the middle ear. [ 2] One of the two main types is acute otitis media ( AOM ), [ 3] an infection of rapid onset that usually presents with ear pain. [ 1] In young children this may result in pulling at the ear, increased crying, and poor sleep. [ 1]
Burow's solution is an aqueous solution of aluminium triacetate. It is available in the U.S. as an over-the-counter drug for topical administration, with brand names including Domeboro (Moberg Pharma), Domeboro Otic (ear drops), Star-Otic, and Borofair. [ 1] The preparation has astringent and antibacterial properties and may be used to treat a ...
Wikiversity has learning resources about Global Audiology. Hearing loss may be caused by a number of factors, including: genetics, ageing, exposure to noise, some infections, birth complications, trauma to the ear, and certain medications or toxins. [ 2] A common condition that results in hearing loss is chronic ear infections. [ 2]
Finafloxacin is used to treat a type of ear infection called acute otitis externa caused by Pseudomonas aeruginosa and Staphylococcus aureus bacteria. [3] In the clinical trial that led to the drug's approval, finafloxacin shortened the time to cessation of ear pain from an average of 6.8 days in patients taking a placebo to 3.5 days.