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Myopia, also known as near-sightedness and short-sightedness, [5] is an eye disease [6] [7] [8] where light from distant objects focuses in front of, instead of on, the retina. [ 1 ] [ 2 ] [ 7 ] As a result, distant objects appear blurry while close objects appear normal. [ 1 ]
The ability to focus on near objects declines throughout life, from an accommodation of about 20 dioptres (ability to focus at 50 mm away) in a child, to 10 dioptres at age 25 (100 mm), and levels off at 0.5 to 1 dioptre at age 60 (ability to focus down to 1–2 m only).
In 2018, Massachusetts Eye and Ear had two adult specialties nationally ranked the "U.S. News Best Hospitals Rankings and Ratings 2018-18, with the Department of Ophthalmology ranked number four in the U.S. and the Department of Otolaryngology placing number six in the nation. [3]
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The pupil of the human eye can range in size from 2 mm to over 8 mm to adapt to the environment. The human eye can detect a luminance from 10 −6 cd/m 2, or one millionth (0.000001) of a candela per square meter to 10 8 cd/m 2 or one hundred million (100,000,000) candelas per square meter.
In one study, 10 people were given two drops of 0.5 mg/mL of tetryzoline eye drops (0.025–0.05 mg) at 0 hrs, 4 hrs, 8 hrs, and 12 hrs. Within a 24-hour time window, since the last dose of tetryzoline, the blood serum concentration of tetryzoline in the test subjects was 0.068-0.380 ng /mL and the urine concentration was 13–210 ng/mL.
The WHO is funded primarily by contributions from member states (both assessed and voluntary), followed by private donors. Its total approved budget for 2020–2021 is over $7.2 billion, [2] [11] while the approved budget for 2022–2023 is over $6.2 billion. The budget is $6.83 billion for 2024–2025.
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