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In one April 2023 study, researchers found that one over-the-counter brand of melatonin gummies had more than four-times as much melatonin as its label said. Several contained both melatonin and ...
The new research shows 6% of kids aged 1-4 had received melatonin supplements in the last month; 18.5% of kids ages 5 to 9 took it, as did 19.4% of kids 10-13.
It has become a popular over-the-counter sleeping aid, with sales increasing 150% between 2016 and 2020, the authors said. In the U.S., melatonin is sold as a supplement, not regulated as a drug.
Melatonin is also available as an over-the-counter dietary supplement in many countries. It is available in both immediate-release and less commonly prolonged-release forms. The compound is available in supplements at doses ranging from 0.3 mg to 10 mg or more. It is also possible to buy raw melatonin powder by the weight. [ 39]
Melatonin, an indoleamine, is a natural compound produced by various organisms, including bacteria and eukaryotes. [ 1] Its discovery in 1958 by Aaron B. Lerner and colleagues stemmed from the isolation of a substance from the pineal gland of cows that could induce skin lightening in common frogs.
Over-the-counter supplements like melatonin may seem benign —but they can pose real dangers, especially to kids. Write to Jeffrey Kluger at jeffrey.kluger@time.com . Show comments
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