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Amphetamine[ note 2] (contracted from a lpha - m ethyl ph en et hyl amine) is a central nervous system (CNS) stimulant that is used in the treatment of attention deficit hyperactivity disorder (ADHD), narcolepsy, and obesity. Amphetamine was discovered as a chemical in 1887 by Lazăr Edeleanu, and then as a drug in the late 1920s. [ 25]
0.8–1.5% (2019, using DSM-IV-TR and ICD-10) [ 2] Attention deficit hyperactivity disorder ( ADHD) is a neurodevelopmental disorder characterised by executive dysfunction occasioning symptoms of inattention, hyperactivity, impulsivity and emotional dysregulation that are excessive and pervasive, impairing in multiple contexts, and ...
A dopamine antagonist, also known as an anti-dopaminergic and a dopamine receptor antagonist ( DRA ), is a type of drug which blocks dopamine receptors by receptor antagonism. Most antipsychotics are dopamine antagonists, and as such they have found use in treating schizophrenia, bipolar disorder, and stimulant psychosis. [ 1]
Apomorphine. Apomorphine, sold under the brand name Apokyn among others, is a type of aporphine having activity as a non- selective dopamine agonist which activates both D 2 -like and, to a much lesser extent, D 1 -like receptors. [ 1] It also acts as an antagonist of 5-HT 2 and α-adrenergic receptors with high affinity.
An operating temperature is the allowable temperature range of the local ambient environment at which an electrical or mechanical device operates. The device will operate effectively within a specified temperature range which varies based on the device function and application context, and ranges from the minimum operating temperature to the maximum operating temperature (or peak operating ...
For the first time in more than 20 years, the convicted murderer of Laci Peterson speaks out in the new Peacock documentary 'Face to Face with Scott Peterson'
Sulpiride is a selective antagonist at dopamine D 2, D 3 and to a lesser extent D 4 receptors. Antagonism at 5-HT 1A dominates in doses exceeding 600 mg daily. In doses of 600 to 1,600 mg sulpiride shows mild sedating and antipsychotic activity. Its antipsychotic potency compared to chlorpromazine is only 0.2 (1/5).
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