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Doxylamine and other first-generation antihistamines are the most widely used sleep medications in the world. [6] Typical side effects of doxylamine (at recommended doses) include dizziness, drowsiness, grogginess, and dry mouth, among others. [7] [4] As an antihistamine, doxylamine is an inverse agonist of the histamine H 1 receptor.
Before taking temazepam, one should ensure that at least 8 hours are available to dedicate to sleep. Failing to do so can increase the side effects of the drug. Like all benzodiazepines, the use of this drug in combination with alcohol potentiates the side effects, and can lead to toxicity and death.
Doxepin is a medication belonging to the tricyclic antidepressant (TCA) [ 10] class of drugs used to treat major depressive disorder, anxiety disorders, chronic hives, and insomnia. [ 10][ 11] For hives it is a less preferred alternative to antihistamines. [ 10] It has a mild to moderate benefit for sleeping problems. [ 12]
Eszopiclone. Eszopiclone, sold under the brand name Lunesta among others, is a medication used in the treatment of insomnia. [ 3][ 4] Evidence supports slight to moderate benefit up to six months. [ 5][ 4][ 6] It is taken by mouth. [ 3][ 5] Common side effects include headache, dry mouth, nausea, and dizziness. [ 5]
Sominex is the trademarked name for several over the counter sleep aids. Different formulations of Sominex are available, depending upon the market. Both the US and UK formulations contain a significant dose of a first generation antihistamine with hypnotic properties. In the United States, Sominex is marketed by Prestige Brands, [ 1] sometimes ...
Zolpidem is a nonbenzodiazepine or Z-drug which acts as a sedative and hypnotic. [ 10][ 17] Zolpidem is a GABA A receptor agonist of the imidazopyridine class. [ 10] It works by increasing GABA effects in the central nervous system by binding to GABA A receptors at the same location as benzodiazepines. [ 10]
Zolpidem tartrate, a common but potent sedative–hypnotic drug.Used for severe insomnia. Hypnotic (from Greek Hypnos, sleep [1]), or soporific drugs, commonly known as sleeping pills, are a class of (and umbrella term for) psychoactive drugs whose primary function is to induce sleep [2] (or surgical anesthesia [note 1]) and to treat insomnia (sleeplessness).
Main side effects of oxycodone [43] Two tablets (10 mg) of oxycodone and safety blisters. Most common side effects of oxycodone include reduced sensitivity to pain, delayed gastric emptying, euphoria, anxiolysis (a reduction in anxiety), feelings of relaxation, and respiratory depression. [44]
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