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As an antihistamine, doxylamine is an inverse agonist of the histamine H 1 receptor. As a first-generation antihistamine, it typically crosses the blood–brain barrier into the brain, thereby producing a suite of sedative and hypnotic effects that are mediated by the central nervous system. (N.b.:
In this select population who are naive to and overdose solely on a benzodiazepine, it can be considered. [53] Due to its short half life, the duration of action of flumazenil is usually less than 1 hour, and multiple doses may be needed. [48] When flumazenil is indicated the risks can be reduced or avoided by slow dose titration of flumazenil ...
Flunitrazepam, sold under the brand name Rohypnol among others, [ 3] is a benzodiazepine used to treat severe insomnia and assist with anesthesia. [ 4] As with other hypnotics, flunitrazepam has been advised to be prescribed only for short-term use or by those with chronic insomnia on an occasional basis.
The tables below contain a sample list of benzodiazepines and benzodiazepine analogs that are commonly prescribed, with their basic pharmacological characteristics, such as half-life and equivalent doses to other benzodiazepines, also listed, along with their trade names and primary uses. The elimination half-life is how long it takes for half ...
Diazepam. Diazepam, sold under the brand name Valium among others, is a medicine of the benzodiazepine family that acts as an anxiolytic. [ 14] It is used to treat a range of conditions, including anxiety, seizures, alcohol withdrawal syndrome, muscle spasms, insomnia, and restless legs syndrome. [ 14]
Fake pills like oxycodone and Xanax can be laced with fentanyl. ... When researchers just looked at Western states, overdose deaths from counterfeit pills more than tripled, from 4.7% in 2019 to ...
A drug overdose ( overdose or OD) is the ingestion or application of a drug or other substance in quantities much greater than are recommended. [ 2][ 3] Typically it is used for cases when a risk to health will potentially result. [ 2] An overdose may result in a toxic state or death. [ 3]
Gannett. Christina Hall, Detroit Free Press. July 27, 2024 at 3:22 PM. A St. Clair Shores doctor who federal prosecutors said operated a "pill mill" and was convicted in a patient's overdose death ...
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