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The Sanofi–GSK COVID‑19 vaccine is a recombinant protein subunit vaccine containing the SARS-CoV-2 spike protein, which is produced in insect cells via a baculovirus vector. It also includes an adjuvant made by GSK. It uses the same technology as Sanofi's Flublok influenza vaccine. [ 7][ 8]
GlaxoSmithKline Pharmaceuticals Ltd is an Indian research-based pharmaceutical and healthcare company, and a subsidiary of GSK. [4] [5] The company's product portfolio includes prescription medicines and vaccines. Its prescription medicines range across therapeutic areas such as anti-infectives, dermatology, gynaecology, diabetes, oncology ...
The main benefit of cell-based vaccines is the ability to rapidly produce vaccine supplies during an impending pandemic. Cell-based antigen production offer a faster and more stable production of vaccines compared to embryonic chicken eggs, which produce 1-2 vaccine doses per chicken egg. [8]
In April, Pfizer said its vaccine succeeded in a trial evaluating it in adults under age 60, adding that it plans to submit for expanded approval of the vaccine in adults aged 18 to 59. GSK also ...
The vaccines are the first approved to prevent RSV, which causes around 14,000 deaths in adults aged 65 and older in the U.S. annually, according to government estimates. US CDC OKs use of new ...
July 26, 2024 at 4:12 AM. (Reuters) -The European Union health regulator on Friday recommended expanded use of GSK's respiratory syncytial virus (RSV) vaccine in adults aged between 50 and 59. Any ...
One issue in developing the vaccine is the need for bark extract from the tree Quillaja saponaria that is used in combination with monophosphoryl lipid A as an immunologic adjuvant. This adjuvant is used by several other GSK vaccines—especially the shingles vaccine that is more profitable—and GSK owns most of the world's supply.
AS03 (for "Adjuvant System 03") is the trade name for a squalene -based immunologic adjuvant used in various vaccine products by GlaxoSmithKline (GSK). It is used, for example, in GSK's A/H1N1 pandemic flu vaccine Pandemrix. It is also in Arepanrix and the Q-pan for H5N1 influenza. [1] A dose of AS03 adjuvant contains [2] In the 2009 influenza ...