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  2. List of drugs granted breakthrough therapy designation

    en.wikipedia.org/wiki/List_of_drugs_granted...

    Amgen. non-small cell lung cancer with KRAS G12C mutation. Avapritinib. Blueprint Medicines Corp. granted for two indications: mast cell leukemia and advanced systemic mastocytosis. Belumosudil. Kadmon Pharmaceuticals. chronic graft-versus-host disease. Pembrolizumab.

  3. List of antiviral drugs - Wikipedia

    en.wikipedia.org/wiki/List_of_antiviral_drugs

    COVID-19. Pfizer. 3C-like protease inhibitor (Nirmatrelvir) / inhibition of metabolism of nirmatrelvir (ritonavir) Nevirapine. HIV. non- nucleoside reverse transcriptase inhibitor. Nitazoxanide. Broad-spectrum antiviral.

  4. Tecovirimat - Wikipedia

    en.wikipedia.org/wiki/Tecovirimat

    Tecovirimat. Tecovirimat, sold under the brand name Tpoxx among others, [6] is an antiviral medication with activity against orthopoxviruses such as smallpox and mpox. [4] [7] [8] In 2018 it became the first antipoxviral drug approved in the United States. [9] [10]

  5. Category:Drugs with unknown mechanisms of action - Wikipedia

    en.wikipedia.org/wiki/Category:Drugs_with...

    This is a category for drugs in which the specific mechanism of action relevant to therapeutic effects is unknown or unclear. Subcategories This category has only the following subcategory.

  6. Eculizumab - Wikipedia

    en.wikipedia.org/wiki/Eculizumab

    Eculizumab, sold under the brand name Soliris among others, is a recombinant humanized monoclonal antibody used to treat paroxysmal nocturnal hemoglobinuria, atypical hemolytic uremic syndrome, generalized myasthenia gravis, and neuromyelitis optica. [8] [9] In people with paroxysmal nocturnal hemoglobinuria, it reduces both the destruction of ...

  7. Semaglutide is linked to a rare eye condition that can cause ...

    www.aol.com/lifestyle/semaglutide-linked-rare...

    Researchers have found a link between semaglutide use and NAION, a rare condition that is the second-leading cause of optic nerve blindness. (Getty Images) (Jacob Wackerhausen via Getty Images)

  8. Dofetilide - Wikipedia

    en.wikipedia.org/wiki/Dofetilide

    Dofetilide is a class III antiarrhythmic agent. [2] It is marketed under the trade name Tikosyn by Pfizer, and is available in the United States in capsules containing 125, 250, and 500 μg of dofetilide. It is not available in Europe [3] or Australia. [4]

  9. List of stringent regulatory authorities - Wikipedia

    en.wikipedia.org/wiki/List_of_stringent...

    List of stringent regulatory authorities. A stringent regulatory authority ( SRA) is a national drug regulation authority which the World Health Organization (WHO) considers to apply stringent standards for quality, safety, and efficacy in its process of regulatory review of drugs and vaccines for marketing authorization. [1]