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Diabetic foot ulcer is a breakdown of the skin and sometimes deeper tissues of the foot that leads to sore formation. It may occur due to a variety of mechanisms. It is thought to occur due to abnormal pressure or mechanical stress chronically applied to the foot, usually with concomitant predisposing conditions such as peripheral sensory neuropathy, peripheral motor neuropathy, autonomic ...
A diabetic foot disease is any condition that results directly from peripheral artery disease (PAD) or sensory neuropathy affecting the feet of people living with diabetes. Diabetic foot conditions can be acute or chronic complications of diabetes. [ 1] Presence of several characteristic diabetic foot pathologies such as infection, diabetic ...
Diabetic foot infection is any infection of the foot in a diabetic person. [3] The most frequent cause of hospitalization for diabetic patients is due to foot infections. [4] Symptoms may include pus from a wound, redness, swelling, pain, warmth, tachycardia, or tachypnea. [5] Complications can include infection of the bone, tissue death ...
Diphenhydramine. Diphenhydramine ( DPH) is an antihistamine and sedative mainly used to treat allergies, insomnia, and symptoms of the common cold. It is also less commonly used for tremors in parkinsonism, and nausea. [ 11] It is taken by mouth, injected into a vein, injected into a muscle, or applied to the skin. [ 11]
Diabetes is the foremost cause in America today for neuropathic joint disease, [1] and the foot is the most affected region. In those with foot deformity, approximately 60% are in the tarsometatarsal joints (medial joints affected more than lateral), 30% metatarsophalangeal joints, and 10% have ankle disease. Over half of diabetic patients with ...
Malum perforans. Malum perforans is a long-lasting, usually painless ulcer that penetrates deep into or through the skin, usually on the sole of the foot (in which case it may be called malum perforans pedis ). It is often a complication in diabetes mellitus and other conditions affecting the nerves. [1]
Levamisole induced necrosis syndrome. Levamisole induced necrosis syndrome ( LINES) [1] is a complication of adulterated cocaine recognized in 2011, caused by the use of levamisole as a cutting agent for cocaine. Spontaneous bruising of the earlobes is considered characteristic of this condition, but lesions can present anywhere on the body.
But antihistamines like promethazine, doxylamine, and diphenhydramine can interfere with your body temperature regulation and tamp down on your ability to sweat, according to the CDC. Stimulants