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Relaxin is a protein hormone of about 6000 Da, [1] first described in 1926 by Frederick Hisaw. [2] [3]The relaxin family peptide hormones belong to the insulin superfamily and consists of seven peptides of high structural but low sequence similarity; relaxin-1 (RLN1), 2 (RLN2) and 3 (), and the insulin-like (INSL) peptides, INSL3, INSL4, INSL5 and INSL6.
Somnifacient (from Latin somnus, sleep [1] ), also known as sedatives or sleeping pills, is a class of medications that induces sleep. It is mainly used for treatment of insomnia. Examples of somnifacients include benzodiazepines, barbiturates and antihistamines . Around 2-6% of adults with insomnia use somnifacients to aid sleep. [2]
Ramelteon is approved for the treatment of insomnia characterized by difficulty with sleep onset in adults. [ 3][ 5] In regulatory clinical trials, it was found to significantly reduce latency to persistent sleep (LPS). [ 3] A 2009 pooled analysis of four clinical trials found that ramelteon at a dose of 8 mg reduced sleep onset by 13 minutes ...
In sleep medicine, we use very small doses of melatonin multiple hours before bed to help gradually shift the body’s clock (circadian rhythm) in people with delayed sleep phase disorder, jet lag ...
Sleep medicine is a medical specialty or subspecialty devoted to the diagnosis and therapy of sleep disturbances and disorders. [1] From the middle of the 20th century, research has provided increasing knowledge of, and answered many questions about, sleep–wake functioning. [2] The rapidly evolving field [3] has become a recognized medical ...
Sominex is the trademarked name for several over the counter sleep aids. Different formulations of Sominex are available, depending upon the market. Both the US and UK formulations contain a significant dose of a first generation antihistamine with hypnotic properties. In the United States, Sominex is marketed by Prestige Brands, [ 1] sometimes ...
As you wait for prescription drug costs to come down from the clouds, here's how you can save money on the medications you need. 1. Use a coupon program. If you don't have insurance, a ...
Eszopiclone is classified as a nonbenzodiazepine or Z-drug and a sedative and hypnotic of the cyclopyrrolone group. [ 7] It is the S- stereoisomer of zopiclone. [ 5][ 8] It works by interacting with the GABA receptors. [ 7] Approved for medical use in the United States in 2004, [ 3] eszopiclone is available as a generic medication. [ 5]
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