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Trodusquemine is a spermine metabolite of cholesterol. The steroid ring consists of a cholestane with a hydroxyl group at C-7 and sulfate group at C-24; spermine is conjugated to the steroid moiety at C-3. It is structurally similar to squalamine, which features a spermidine moiety instead of spermine. [ 3]
Puberty blockers (also called puberty inhibitors or hormone blockers) are medicines used to postpone puberty in children. The most commonly used puberty blockers are gonadotropin-releasing hormone (GnRH) agonists, which suppress the natural production of sex hormones, such as androgens (e.g. testosterone) and estrogens (e.g. estradiol ). [ 1 ...
Vinpocetine. US: Unapproved "New Drug" (as defined by 21 U.S. Code § 321 (p) (1)). Use in dietary supplements, food, or medicine is unlawful; otherwise uncontrolled. [ 2] Vinpocetine ( ethyl apovincaminate) is a synthetic derivative of the vinca alkaloid vincamine, differing by the removal of a hydroxyl group and by being the ethyl rather than ...
Nortriptyline, sold under the brand name Aventyl, among others, is a tricyclic antidepressant. This medicine is also sometimes used for neuropathic pain, attention deficit hyperactivity disorder (ADHD), smoking cessation and anxiety. [ 5][ 6] As with many antidepressants, its use for young people with depression and other psychiatric disorders ...
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Oral rehydration therapy ( ORT) is a type of fluid replacement used to prevent and treat dehydration, especially due to diarrhea. [ 1] It involves drinking water with modest amounts of sugar and salts, specifically sodium and potassium. [ 1] Oral rehydration therapy can also be given by a nasogastric tube. [ 1]
Mayo Clinic is a nonprofit hospital system with campuses in Rochester, Minnesota; Scottsdale and Phoenix, Arizona; and Jacksonville, Florida. [ 22][ 23] Mayo Clinic employs 76,000 people, including more than 7,300 physicians and clinical residents and over 66,000 allied health staff, as of 2022. [ 5] In addition, Mayo Clinic partially owns and ...
The association said that “one key question” taken up by the roundtable was whether ARIA was a temporary symptom of the new drug — much the way nausea and hair loss are side effects of ...